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(Cilastatin)

Font Size: [Big][Mid][Small] 2016-4-11    Views: 604    



Product Name:Cilastatin

English-name:(z)-7-[(2s)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1s)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid

Cas no:82009-34-5

Purpose: pharmaceutical intermediates

 

Item

Standard

Appearance

White to light yellowish powder

Identification

IR

Water(K.F.)

2.0%Max


Absorbency

350nm

0.38Au

380nm

≤0.25Au

430nm

≤0.08Au

Specific optical rotation

+44.0~+49.0

Assay

HPLC

99.4%

Titration

99.0%~101.5%

Heavy metals

≤20ppm

Ash

≤0.1%



Related substance

Impurity A intemediate

0.10%

Unknown single impurity

≤0.09%

Total Impurities

≤0.8%


Residual

solvents

Methanol

167ppm

Acetone

≤2000ppm

Dichloromethane

≤400ppm

Mesityl oxide

≤2000ppm


Bacterial Endotoxins

≤0.10EU/mg

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